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Abstract #2219

Evaluation of Two Susceptibility-Weighted Sequences for Detection of Cerebral Microbleeds

Cheryl R McCreary 1,2 , M Louis Lauzon 1,2 , Saima Batool 1,2 , Eric E Smith 1,2 , and Richard Frayne 1,2

1 Radiology and Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada, 2 Seaman Family MR Centre, Foothills Medical Centre, Calgary, Alberta, Canada

Quantitative susceptibility mapping (QSM) is a method that can be used to identify iron accumulation in the brain, which is a potential marker of neurodegeneration in aging. In an ongoing longitudinal study, susceptibility weighted imaging (SWI) is used for the identification of cerebral microbleeds (CMBs). In this study, we evaluate cerebral microbleed (CMB) detection on susceptibility-weighted images and images from single-echo data (SWI6e) collected from a multi-echo spoiled gradient echo sequence that can be used for quantitative susceptibility mapping. The CMB contrast was lower and the number of CMBs detected was underestimated in SWI6e images compared to SWI.

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