Abstract #2219
Evaluation of Two Susceptibility-Weighted Sequences for Detection of Cerebral Microbleeds
Cheryl R McCreary 1,2 , M Louis Lauzon 1,2 , Saima Batool 1,2 , Eric E Smith 1,2 , and Richard Frayne 1,2
1
Radiology and Clinical Neurosciences,
Hotchkiss Brain Institute, University of Calgary,
Calgary, Alberta, Canada,
2
Seaman
Family MR Centre, Foothills Medical Centre, Calgary,
Alberta, Canada
Quantitative susceptibility mapping (QSM) is a method
that can be used to identify iron accumulation in the
brain, which is a potential marker of neurodegeneration
in aging. In an ongoing longitudinal study,
susceptibility weighted imaging (SWI) is used for the
identification of cerebral microbleeds (CMBs). In this
study, we evaluate cerebral microbleed (CMB) detection
on susceptibility-weighted images and images from
single-echo data (SWI6e) collected from a multi-echo
spoiled gradient echo sequence that can be used for
quantitative susceptibility mapping. The CMB contrast
was lower and the number of CMBs detected was
underestimated in SWI6e images compared to SWI.
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