Abstract #2245
Evaluating brain metabolites in patients with glioma using short and long TE MRSI at 3T and 7T
Yan Li 1 , Marisa Lafontaine 1 , Susan Chang 2 , and Sarah J Nelson 1,3
1
Department of Radiology and Biomedical
Imaging, University of California, San Francisco,
California, United States,
2
Deparmenf
of Neurological Surgery, University of California, San
Francisco, California, United States,
3
Department
of Bioengineering and Therapeutic Sciences, University
of California, San Francisco, California, United States
The purpose of this study was to compare the metabolite
profiles that were acquired using conventional long echo
time MRSI at 3T with short echo time MRSI at 3T and 7T
in patients with glioma. The differences in Cho, Cr and
NAA between acquisitions define the critical role of
relaxation times in defining the observed signals. With
improved quantification and metabolite detection using
short echo time MRSI sequence at 7T, it would be
possible to examine heterogeneity in T2 but the
acquisition is limited in terms of tumor coverage
compared to MRSI at 3T.
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