Abstract #2269
Study of contrast-enhanced T1-w MRI markers of cerebral radiation necrosis manifested in head-and-neck cancers, primary, and metastatic brain tumors: Preliminary findings
Prateek Prasanna 1 , Pallavi Tiwari 1 , Archana Siddalingappa 2 , Leo Wolansky 2 , Lisa Rogers 2 , Tai-Chung Lam 3 , Victoria To 3 , and Anant Madabhushi 1
1
Case Western Reserve University, Cleveland,
OH, United States,
2
University
Hospitals, Cleveland, OH, United States,
3
Tuen
Mun Hospital, Hong Kong, China
In this work, we present the initial results of studying
imaging differences of cerebral radiation necrosis on
Gadolinium contrast-enhanced (Gd-C) T1-w MRI obtained
from a unique cohort of patients treated for (a)
nasopharyngeal carcinoma, (b) Glioblastoma Multiforme (GBM),
and (c) metastatic brain tumors. Ability to identify
changes in imaging characteristics on pure Radiation
Necrosis (RN) with no cancer presence as observed in
nasopharyngeal carcinoma, may allow for improved
understanding of the changes in imaging characteristics
on mixed RN on account of cancer presence in primary
and metastatic brain tumors
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