Functional Connectivity Changes in the Presence of Brain Tumors
Noora Pauliina Tuovinen 1 , Francesco de Pasquale 1 , and Umberto Sabatini 1
Radiology, Santa Lucia Foundation, Rome,
For studying the effects of brain tumors on functional
connectivity, resting state scans were acquired on 10
post-surgical glioblastoma multiforme patients. We
hypothesized that the presence of tumor would affect the
overal connectivity in the brain compared to healthy
subjects. We ran ICA to recognize resting state networks
across patients and defined nodes that were used to run
the connectivity analysis. The data was analyzed using
tools provided by FSL and Matlab. The results revealed
reduced connectivity in the patients.
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