Functional Connectivity Changes in the Presence of Brain Tumors

For studying the effects of brain tumors on functional connectivity, resting state scans were acquired on 10 post-surgical glioblastoma multiforme patients. We hypothesized that the presence of tumor would affect the overal connectivity in the brain compared to healthy subjects. We ran ICA to recognize resting state networks across patients and defined nodes that were used to run the connectivity analysis. The data was analyzed using tools provided by FSL and Matlab. The results revealed reduced connectivity in the patients.

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