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Abstract #2346

Caipirinha acceleration for intracranial 3D DCE MRI: Determination of the optimal sampling pattern

Michael Ingrisch 1 , Michael Peller 1 , Birgit Ertl-Wagner 2 , Maximilian F Reiser 2 , and Olaf Dietrich 1

1 Josef-Lissner-Laboratory for Biomedical Imaging, Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Mnchen, Germany, 2 Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Mnchen, Germany

Acceleration of the image acquisition is an ever important technique in dynamic contrast-enhanced (DCE) MRI. Conventional parallel imaging is limited by the SNR loss at higher acceleration factors and by potential reconstruction artefacts. A recently introduced method, CAIPIRINHA, promises a more robust image reconstruction by modifying the k-space sampling schema. In the present study, we perform phantom measurements to identify the optimal CAIPIRINHA sampling pattern for a 3D DCE MRI perfusion measurement with coverage of the entire neurocranium at high temporal resolution, and we demonstrate the application of CAIPIRINHA acceleration for cerebral DCE MRI in patient measurements

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