Abstract #2360
Feasibility of renal perfusion imaging using velocity selective ASL
Marijn van Stralen 1 , Margreet F Sanders 2 , Hanke J Schalkx 3 , Maurice A van den Bosch 3 , Clemens Bos 4 , Peter J Blankestijn 2 , Tim Leiner 3 , and Esben Thade Petersen 3
1
Image Sciences Institute, UMC Utrecht,
Utrecht, Utrecht, Netherlands,
2
Dept
of Nephrology, UMC Utrecht, Utrecht, Netherlands,
3
Dept
of Radiology, UMC Utrecht, Utrecht, Netherlands,
4
Image
Sciences Institute, UMC Utrecht, Utrecht, Netherlands
Renal perfusion imaging using contrast media injection
is potentially nephrotoxic. Arterial spin labeling
(ASL), employing endogenous contrast, was shown using
pulsed and pseudo-continuous labeling strategies. We
investigated the feasibility of velocity selective ASL
(VS-ASL), which eliminates label planning and possibly
improves perfusion SNR by labeling closer to the target
tissue. We show that renal VS-ASL is feasible, clearly
showing the expected corticomedullary perfusion
distribution in healthy volunteers. However, VS-ASL is
sensitive to motion, especially during labeling. It
could benefit from outlier rejection techniques or
prospective and retrospective motion correction.
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