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Abstract #2360

Feasibility of renal perfusion imaging using velocity selective ASL

Marijn van Stralen 1 , Margreet F Sanders 2 , Hanke J Schalkx 3 , Maurice A van den Bosch 3 , Clemens Bos 4 , Peter J Blankestijn 2 , Tim Leiner 3 , and Esben Thade Petersen 3

1 Image Sciences Institute, UMC Utrecht, Utrecht, Utrecht, Netherlands, 2 Dept of Nephrology, UMC Utrecht, Utrecht, Netherlands, 3 Dept of Radiology, UMC Utrecht, Utrecht, Netherlands, 4 Image Sciences Institute, UMC Utrecht, Utrecht, Netherlands

Renal perfusion imaging using contrast media injection is potentially nephrotoxic. Arterial spin labeling (ASL), employing endogenous contrast, was shown using pulsed and pseudo-continuous labeling strategies. We investigated the feasibility of velocity selective ASL (VS-ASL), which eliminates label planning and possibly improves perfusion SNR by labeling closer to the target tissue. We show that renal VS-ASL is feasible, clearly showing the expected corticomedullary perfusion distribution in healthy volunteers. However, VS-ASL is sensitive to motion, especially during labeling. It could benefit from outlier rejection techniques or prospective and retrospective motion correction.

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