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Abstract #2692

Atherosclerotic plaques affect resting myocardial blood flow quantification using contrast-enhanced magnetic resonance perfusion imaging

Karsten Sommer 1,2 , Dominik Bernat 1 , Regine Schmidt 1 , and Laura M. Schreiber 1

1 Department of Radiology, Johannes Gutenberg University Medical Center, Mainz, Rhineland-Palatinate, Germany, 2 Max Planck Graduate Center with the Johannes Gutenberg University Mainz, Mainz, Rhineland-Palatinate, Germany

The influence of atherosclerotic plaques on bolus dispersion in contrast-enhanced myocardial perfusion imaging has not yet been studied in detail. In this contribution, we use computational fluid dynamics simulations in a high-detailed coronary vascular model to study the impact of both stenosis grade and morphology on bolus dispersion and, consequently, on MBF quantification.

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