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Abstract #2761

Diffusion tensor imaging of thirty-five anisotropic DTI phantoms for CENTER-TBI

Pim Pullens 1 , Michael Bach 2 , Bram Stieltjes 3 , Dirk Smeets 4 , and Paul M Parizel 1

1 Radiology, University Hospital Antwerp & University of Antwerp, Antwerp, Antwerp, Belgium, 2 Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, 3 Radiology, Universittsspital Basel, Basel, Switzerland, 4 icoMetrix, Leuven, Belgium

For CENTER-TBI, a large European multi-center study on Traumatic Brain Injury, diffusion tensor imaging (DTI) is one of the main imaging modalities. 35 clinical sites across Europe will be included to participate in the MRI study. To be able to acquire DTI data that is cross-site comparable it is of fundamental importance to assess the quality and variability of DTI measurements across sites. In this work 35 anisotropic phantoms were produced and evaluated in order to construct a set of baseline measurements. There is a considerable range of FA values between phantoms, but this may be attributed to post-processing and/or partial volume effects.

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