Eddy Current Compensation for Double Wave Vector Diffusion MRI

Double wave vector diffusion MRI gives the opportunity to measure microscopic anisotropy, what, however, requires to reliably acquire diffusion weighted images with many diffusion encoding directions. This in turn might lead to problems in determining trustworthy values because of eddy current induced image distortions. We present a sequence design that compensates for eddy currents, by using additional refocussing pulses and bipolar gradients. We show the effectivity of our sequence by determining the coefficient of variation of the signal intensity over 36 diffusion direction combinations. Additionally we present evidence that eddy current compensation is needed to determine reliable anisotropy values in-vivo.

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