Abstract #2882
Accelerated motion-robust non-Cartesian multi-shot diffusion-weighted imaging with reconstruction in the image space
Benoit Scherrer 1 , Ali Gholipour 1 , Onur Afacan 1 , Sanjay P. Prabhu 1 , and Simon K. Warfield 1
1
Harvard Medical School, Boston Children's
Hospital, Boston, Massachusetts, United States
We propose a novel non-Cartesian multi-shot DWI
technique that achieves high resolution dense k-space
sampling by acquisition of multiple anisotropically
oversampled acquisitions (so-called "shots") and by
reconstruction in the image space. Our approach
leverages the coupling between DW images by
simultaneously performing model-based HR reconstruction
and estimation of a diffusion compartment imaging (DCI)
tissue model that describes the local tissue
microstructure at each voxel. Our combined approach also
enables reconstruction from shots with different subsets
of gradients, providing robustness to patient motion and
potential for acceleration.
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