Variable sample density at high b-values for Radial Diffusion Spectrum Imaging improves angular resolution
Steven Baete 1,2 and Fernando Emilio Boada 1,2
Center for Advanced Imaging Innovation and
Research (CAI2R), NYU School of Medicine, New York, NY,
for Biomedical Imaging, Dept. of Radiology, NYU School
of Medicine, New York, NY, United States
The angular resolution of Diffusion Spectrum Imaging (DSI)
is crucial in accurately determining the complex
distributions of intravoxel fiber orientations in the
human brain. The recently proposed Radial q-space
sampling for DSI (RDSI) has been shown to have improved
angular resolution over conventional Cartesian sampling.
Further improvements in Orientation Distribution
Function (ODF) sampling and angular resolution of DSI
can be obtained by optimizing q-space sampling density
in RDSI. This can be done using variable density in
q-space to minimize the ODF variance, which does not
require extra time when a RDSI multi-echo stimulated
echo sequence is used.
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