Correcting for perfusion and isotropic free diffusion in diffusion weighted imaging and DTI and CSD analysis

In this study, we have investigated the use of Intra voxel incoherent motion (IVIM) modeling in combination with moment nulled diffusion gradients to correct DW imaging data for perfusion and partial volume effects and have tested this method using diffusion tensor imaging (DTI) and constrained spherical deconvolution (CSD) analysis. We have shown that using Asymmetric bipolar diffusion gradients in combination with IVIM correction this bias can be minimized. Furthermore, using 2nd order moment nulled DW sequences prevents signal attenuation due to intra voxel de-phasing originating from velocity and acceleration gradients within a voxel resulting in more reliable IVIM fits.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.