Abstract #3004
Diffusion tensor imaging of forearm nerves for early diagnosis of multifocal motor neuropathy
Wieke Haakma 1,2 , Bas Jongbloed 3 , Martijn Froeling 1 , Clemens Bos 1 , Stephan H. Goedee 3 , Michael Pedersen 4 , Ludo van der Pol 3 , Alexander Leemans 5 , and Jeroen Hendrikse 1
1
Department of Radiology, University Medical
Center Utrecht, Utrecht, Utrecht, Netherlands,
2
Department
of Forensic Medicine & Comparative Medicine Lab, Aarhus
University, Aarhus, Central Denmark, Denmark,
3
Department
of Neurology, University Medical Center Utrecht,
Utrecht, Utrecht, Netherlands,
4
Department of
Clinical Medicine - Comparative Medicine Lab, Aarhus
University, Aarhus, Central Denmark, Denmark,
5
Image
Sciences Institute, University Medical Center Utrecht,
Utrecht, Utrecht, Netherlands
Multifocal motor neuropathy (MMN) is a rare
immune-mediated disorder that affects 1-2 person per
100.000. Due to the progressive pure motor weakness, MMN
is often confused with amyotrophic lateral sclerosis
(ALS). Diffusion tensor imaging (DTI) can be helpful in
evaluating changes of diffusion values, which may aid in
this discrimination. We studied DTI of the forearm
nerves in patients with MMN, ALS and healthy controls.
MMN patients revealed decreased fractional anisotropy
and axial diffusivity compared to healthy controls.
These preliminary results indicate a potential role of
DTI in discriminating between MMN and ALS.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
