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Abstract #3018

Impact of Co-Registration on the Histogram Analysis of ADC maps in MRI/MRS Brain Tumor Diagnostics

Nuno Pedrosa de Barros 1,2 , Urspeter Knecht 2 , Roland Wiest 2 , and Johannes Slotboom 2

1 University of Bern, Bern, Bern, Switzerland, 2 Institute for Diagnostic and Interventional Neuroradiology, Bern, Bern, Switzerland

MR-spectroscopy and MR-diffusion have proven to provide important information for initial brain tumor diagnostics as well as for tumor progression evaluation. For advanced longitudinal analysis of brain tumor patients, tools enabling combined advanced image and spectral analysis including co-registration are of utmost importance. However, image co-registration may have negative impact on the information extracted from ADC-maps. This study analysed the impact of co-registration on the histogram analysis of ADC maps of brain tumor patients examined by MRS.

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