Impact of Co-Registration on the Histogram Analysis of ADC maps in MRI/MRS Brain Tumor Diagnostics
Nuno Pedrosa de Barros 1,2 , Urspeter Knecht 2 , Roland Wiest 2 , and Johannes Slotboom 2
University of Bern, Bern, Bern, Switzerland,
for Diagnostic and Interventional Neuroradiology, Bern,
MR-spectroscopy and MR-diffusion have proven to provide
important information for initial brain tumor
diagnostics as well as for tumor progression evaluation.
For advanced longitudinal analysis of brain tumor
patients, tools enabling combined advanced image and
spectral analysis including co-registration are of
utmost importance. However, image co-registration may
have negative impact on the information extracted from
ADC-maps. This study analysed the impact of
co-registration on the histogram analysis of ADC maps of
brain tumor patients examined by MRS.
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