New Mathematical Model for the Diffusion Time Dependent ADC

DMRI has been established as a useful tool to obtain voxel-level information on tissue microstructure. An important quantity measured in dMRI is the apparent diffusion coefficient (ADC), and it has been well established by in-vivo brain imaging experiments that the ADC depends significantly on the diffusion time. To aid in understanding and interpreting the experimentally measured ADC, we derive a new mathematical model of the voxel-level ADC that is diffusion time-dependent and accurate over a large range of diffusion times, using a linearization of the Bloch-Torrey equation around low b-values. The goal is to use this time-dependent ADC model in the future to identify parameters of tissue microstructure from the experimentally measured ADC at different diffusion times.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.