Meeting Banner
Abstract #3259

Explicit modeling of SPGR signals using Extended Phase Graphs in DESPOT style relaxometry - a Dictionary approach

Rui Pedro A. G. Teixeira 1,2 , Shaihan J. Malik 1,2 , and Joseph V. Hajnal 1,2

1 Center for the Developing Brain, King's College London, London, United Kingdom, 2 Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom

The DESPOT method for measuring T1 and T2 provides efficient high resolution mapping that is widely used in brain studies, but is regarded as at risk of overestimating relaxation time values compared to more conventional slower methods. We hypothesized that this could be caused by imperfect spoiling of the T1 weighted spoiled gradient echo sequences used. We explored a dictionary based fitting approach in which the SPGR signal is explicitly modeled using an extended phase graph. Results suggest that while the method allows fitting with lower residuals, resulting parameters values are not significantly changed.

This abstract and the presentation materials are available to members only; a login is required.

Join Here