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Abstract #3260

Heat Induced Contrast Mechanisms in MRI: in vivo Tissue Characterization by MR Thermal Response

Matthew Tarasek 1 , Oguz Akin 2 , Jeannette Christine Roberts 3 , Tom Foo 1 , and Desmond T.B. Yeo 1

1 MRI, GE Global Research, Niskayuna, NY, United States, 2 Radiology, MSKCC, New York, NY, United States, 3 Imaging & Physiology Lab, GE Global Research, Niskayuna, NY, United States

MR imaging provides excellent spatial resolution and anatomical soft tissue contrast, yet there are still limitations in detecting and delineating early-stage cancer lesions when they are curable. In hopes of extending ideas for a multiparametric, quantitative MRI data set, we evaluated a unique approach for MR contrast by utilizing the thermal responses of heat-sensitive MR parameters. We look for the accuracy and repeatability in measuring these parameters, and evaluate if heat-induced contrast mechanisms have the potential to add information to conventional MR imaging contrast types for better identification and characterization of in vivo tumors.

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