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Abstract #3261

IR-MRI layers of the visual cortex in Congenitally blind Subjects

Daniel Barazany 1,2 , Ella Striem-Amit 3 , Shani Ben Amitay 1 , Amir Amedi 3 , and Yaniv Assaf 1

1 Neurobiology, Tel Aviv University, Tel Aviv, Israel, 2 CUBRIC School of Psychology, Cardiff University, Cardiff, United Kingdom, 3 Medical Neurobiology, The Hebrew University of Jerusalem, Jerusalem, Israel

IR-MRI provides enhanced image intensity in the human cortex that enables its subdivision to laminar shaped clusters. These clusters reflect cytoarchitectonic organization in the cortex, which could be further used for visualizing and quantifying changes due to brain impairment. In this study, IR-MRI analysis framework was employed on congenitally blind and sighted control subjects focusing on the visual cortices (V1 and V2). We explored the clusters composition on each region, aiming to expose microstructural differences originating probably from lack of input to the visual cortex as occurred in blindness.

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