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Abstract #3263

Synthetic MP-RAGE anatomies with pure T1-weighting improve the detectability of brain tumors

Ulrike Noeth 1 , Elke Hattingen 2 , Oliver Baehr 3 , Julia Tichy 3 , and Ralf Deichmann 1

1 Brain Imaging Center (BIC), Goethe University Frankfurt/Main, Frankfurt/Main, Germany, 2 Institute of Neuroradiology, University Hospital Frankfurt/Main, Germany, 3 Dr Senckenberg Institute of Neurooncology, Goethe University Frankfurt/Main, Germany

Synthetic MP-RAGE anatomies were calculated from quantitative parameter maps (T1, PD, and RF coil bias) and the influence of these parameters on MP-RAGE image contrasts is discussed. Acquired and synthetic data are analyzed for SNR, CNR, and optical contrasts. In contrast to conventional anatomies with mixed contrasts, purely T1-weighted synthetic anatomies show significantly higher optical contrasts and improved visibility of tumor and edema in patients with high grade glioma.

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