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Abstract #3281

Quantitative T 2 and T 2 * relaxometry of hippocampal subfields

Md Nasir Uddin 1 , Yushan Huang 2 , Nikolai V Malykhin 1,2 , and Alan H Wilman 1

1 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada, 2 Centre for Neuroscience, University of Alberta, Edmonton, Alberta, Canada

Hippocampal subfields are affected selectively in different disease processes but the interpretations are mostly limited to accurate volume measurements. Quantitative T 2 or T 2 * relaxometry using high field MRI may be a more sensitive measure for hippocampal subfields compared to volumetric measurements. Here we investigate the absolute measures of spin-echo T 2 and gradient-echo T 2 * of the hippocampal subfields at 4.7 T using stimulated echo compensation and susceptibility compensation.

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