Abstract #3365
Magnetization transfer ratio (MTR) imaging in the presence of fat
James H Holmes 1 , Kevin M Johnson 2 , Diego Hernando 3 , Scott B Reeder 2,3 , and Alexey Samsonov 3
1
Global MR Applications and Workflow, GE
Healthcare, Madison, WI, United States,
2
Medical
Physics, University of Wisconsin-Madison, Madison, WI,
United States,
3
Radiology, University of
Wisconsin-Madison, Madison, WI, United States
Magnetization transfer (MT) imaging is challenging in
the presence of fatty tissues due to the absence of an
MT effect in fat as well as the interference between fat
and MT-attenuated water signal due to chemical shift. We
demonstrate a method that improves MT imaging in the
presence of fat by combining MT with a multi-echo
chemical shift encoded technique. Results in phantoms
demonstrate more robust MT ratios despite the presence
of fat. In vivo results show improved stability of MTR
measurements in fat containing tissues including fatty
liver disease.
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