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Abstract #3441

Resting State Network Development in Very Preterm Infants

Lili He 1 and Nehal A. Parikh 1,2

1 Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States, 2 Department of Pediatrics, The Ohio State University College of Medicine, Columubs, Ohio, United States

Resting-state functional connectivity MRI is a task-free tool that can be safely performed in infants soon after birth to gain insights into functional brain networks associated with motor, cognitive, and behavioral development. In our present longitudinal study, we followed a cohort of very preterm infants soon after birth to identify the perinatal developmental windows for major resting state networks and explore their maturation through three months corrected age. We observed the presence of several important networks, resembling patterns observed in adults, in very preterm infants. Additionally, most of the networks demonstrated an increase in connection strength with advancing postnatal age.

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