Abstract #3537
Acute Effect of Methadone Maintenance Dose on Cerebral Blood Flow in Heroin Users under Methadone Maintenance Treatment
Chien-Yuan Eddy Lin 1,2 , I-Hsiao Yang 3,4 , Hsiu-Ling Chen 3,4 , Meng-Chang Tsai 5 , Pei-Chin Chen 3,4 , Meng-Hsiang Chen 3,4 , and Wei-Che Lin 3,4
1
GE Healthcare, Taipei, Taiwan,
2
GE
Healthcare China, Beijing, China,
3
Department
of Diagnostic Radiology, Kaohsiung Chang Gung Memorial
Hospital, Kaohsiung, Taiwan,
4
Chang
Gung University College of Medicine, Kaohsiung, Taiwan,
5
Department
of psychiatry, Kaohsiung Chang Gung Memorial Hospital,
Kaohsiung, Taiwan
Alteration of cerebral blood flow (CBF) in heroin users
under methadone maintenance treatment (MMT) had been
reported but the acute effect before and after methadone
administration is still less known. The purpose of this
study is to investigate the acute changes of CBF in MMT
subjects one hour before and after methadone
administration by using arterial spin labeling perfusion
MRI, and their relationships with history of heroin
usage and methadone treatment.
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