Abstract #3556
Multi-modal pattern recognition: an application to schizophrenia.
Orla M Doyle 1 , Brandon Whitcher 2,3 , Steven C.R. Williams 1 , Mitul A Mehta 1 , and Stephen M Lawrie 4
1
Dept of Neuroimaging, IoPPN, King's College
London, London, United Kingdom,
2
Clinical
& Translational Imaging, Pfizer, Cambridge, MA, United
States,
3
Dept
of Mathematics, Imperial College London, London, United
Kingdom,
4
Division
of Psychiatry, University of Edinburgh, Edinburgh,
United Kingdom
This is the first time that structural brain data, rCBF
and MRS data have been jointly assessed for
discriminating schizophrenia from controls. Twenty-four
patients diagnosed with schizophrenia and 24 age- and
gender-matched controls were included. An increase in
discriminative power was not observed on combining
modalities. rCBF was the most highly weighted modality.
Predictive probabilities (the probability of belonging
to the SCZ group) were not correlated with the level of
antipsychotic medication. These results imply that
perfusion imaging is a highly sensitive marker for
schizophrenia. Future work should assess the specificity
via differential diagnosis of psychiatric disorders.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
