Abstract #3572
Influence of a severe internal carotid artery stenosis on diffusion and perfusion values in acute stroke patients
Philipp Kaesemann 1 , Gtz Thomalla 2 , Bastian Cheng 2 , Andras Treszl 3 , Jens Fiehler 4 , and Nils Daniel Forkert 5
1
Department of Computational Neuroscience,
University Medical Center Hamburg-Eppendorf, Hamburg,
Germany,
2
Department
of Neurology, University Medical Center
Hamburg-Eppendorf, Germany,
3
Department
of Medical Biometrics and Epidemiology, University
Medical Center Hamburg-Eppendorf, Germany,
4
Department
of Diagnostic and Interventional Neuroradiology,
University Medical Center Hamburg-Eppendorf, Germany,
5
Department
of Radiology and Hotchkiss Brain Institute, University
of Calgary, Calgary, Alberta, Canada
The effect of a long-lasting internal carotid artery
(ICA) stenosis on the diffusion and perfusion situation
in patients with an acute ischemic stroke is not well
understood. Within this context, it may be hypothesized
that an ICA stenosis leads to a more severe
hypoperfusion situation. On the other hand, an ICA
stenosis may be even beneficial in case of an acute
stroke due to a prior development of an improved
collateral situation or preconditioning of the brain
tissue. The objective of this study was to compare
lesion volumes as well as diffusion and perfusion
parameters in acute ischemic stroke patients with or
without a coexisting ICA stenosis.
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