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Abstract #3577

Diffusion Lesion Characteristics after Thrombolysis Treatment in Ischemic Stroke

Venkata Veerendra Nadh Chebrolu 1 , Dattesh Shanbhag 1 , Patrice Hervo 2 , Marc-Antoine Labeyrie 3 , Catherine Oppenheim 3 , and Rakesh Mullick 4

1 Medical Image Analysis Lab, GE Global Research, Bangalore, Karnataka, India, 2 GE Healthcare, Buc, France, 3 Centre Hospitalier, Sainte-Anne, Paris, France, 4 Diagnostics & Biomedical Technologies, GE Global Research, Bangalore, Karnataka, India

Multiple approaches have been proposed for segmenting the diffusion lesion in the acute phase of the ischemic stroke. The same algorithms may not be accurate for segmenting the diffusion lesion on the data obtained one day after treatment (day 1 diffusion lesion). In this work, we analyze the diffusion lesions apparent diffusion coefficient (ADC) and DWI characteristics after treatment and compare them with the diffusion lesion characteristics within 4.5 hours of ictus (day 0 diffusion lesion). We also analyze the sensitivity and specificity of different linear classification methods in segmenting the day 1 diffusion lesion using Receiver Operating Characteristic analysis.

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