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Abstract #3753

Improving T 2 * mapping accuracy by spatially adaptive non local means noise filtering

Till Huelnhagen 1 , Andreas Pohlmann 1 , and Thoralf Niendorf 1,2

1 Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine (MDC), Berlin, Germany, 2 Experimental and Clinical Research Center, a joint cooperation between the Charite Medical Faculty and the Max-Delbrueck Center, Berlin, Germany

This works investigates the impact of spatially adaptive non local means filtering (SANLM) on T 2 * mapping accuracy using numerical simulations and in vivo data derived from animal and human imaging at ultrahigh magnetic fields. The presented results suggest, that SANLM filtering prior to T 2 * mapping can substantially improve T 2 * fitting accuracy, but should be used with due caution for very small structures and very low SNR. The in vivo results suggest that SANLM filtering provides means for improving parametric mapping for a broad range of applications including neurovasculaar and cardiac parametric mapping.

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