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Abstract #3867

The diagnostic performance of hybrid FDG-PET/MR compared to FDG-PET/CT in adult lymphoma patients

Alexander R Guimaraes 1,2 , Wendy Atkinson 3 , Ephraim Hochberg 4 , Jeremy Abramson 5 , Onofrio Catalano 2 , Bruce R Rosen 2 , and Ciprian Catana 2

1 Radiology, Oregon Health Sciences University, Portland, OR, United States, 2 Radiology, Martinos Center for Biomedical imaging, Charlestown, MA, United States, 3 Radiology, Martinos Center for Biomedical imaging, Charlesown, MA, United States, 4 Medicine, Massachusetts General Hospital, Boston, MA, United States, 5 Medicine, Massachusetts General Hospital, MA, United States

FDG-PET/CT has become an essential tool in the initial staging of Hodgkin lymphoma and aggressive non-Hodgkin lymphomas. In select histologies, early interim PET/CT has also shown to be a strong independent predictor of outcome. Hybrid PET/MR imaging is a novel imaging modality that offers improved soft tissue contrast, conspicuity of bone marrow infiltration, diffusion weighted imaging, and lower radiation dose: all factors that could have dramatic impact in the management of lymphoma. The overarching goal of this work was to test the hypothesis that PET/MRI offers an equivalent qualitative and quantitative imaging staging algorithm to PET/CT, but with decreased-risk of late radiation-associated toxicities.

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