Abstract #3984
Parallel Imaging for Short Breath Hold Times in Perfluorinated Gas Imaging of the Lung
Hal Cecil Charles 1 , Randall W. Jones 2 , Ahmed F. Halaweish 3 , and Maureen D. Ainslie 1
1
Radiology, Duke Image Analysis Laboratory,
Duke University Medical School, Durham, NC, United
States,
2
ScanMed,
Omaha, Nebraska, United States,
3
Currently at
Siemens Healthcare, MN, United States
Airway diseases (e.g. COPD and asthma) represent an
economic burden in the US of approximately $100 billion
annually and up to $90 billion annually, respectively.
In order to fully understand lung function in airway
disease a major challenge lies in the regional
determination of poorly ventilated compartments in the
lung. We have developed a method of imaging gas wash-in
and wash-out that gives us a quantitative measure of
mechanical ventilation the rate of gas replacement
normalized to gas volume. We have implemented parallel
imaging of perfluorinated gas/oxygen mixtures to shorten
breath hold times in subjects with severe lung disease.
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