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Abstract #3990

Pulmonary time constant of oxygen consumption evaluated by hyperpolarized 129 Xe MR

Haidong Li 1 , Zhiying Zhang 1 , Xiuchao Zhao 1 , Xianping Sun 1 , Chaohui Ye 1 , and Xin Zhou 1

1 National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, China

We proposed a new method to evaluate the lung function by measuring the time constant of oxygen consumption (T O-C ) in the lung with hyperpolarized xenon MR. It demonstrated that such time constant has a significant difference between COPD and healthy rats, and we believe this parameter is helpful to quantify the oxygen concentration in oxygen therapy of patients.

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