Abstract #3990
Pulmonary time constant of oxygen consumption evaluated by hyperpolarized 129 Xe MR
Haidong Li 1 , Zhiying Zhang 1 , Xiuchao Zhao 1 , Xianping Sun 1 , Chaohui Ye 1 , and Xin Zhou 1
1
National Center for Magnetic Resonance in
Wuhan, Wuhan Institute of Physics and Mathematics,
Chinese Academy of Sciences, Wuhan, Hubei, China
We proposed a new method to evaluate the lung function
by measuring the time constant of oxygen consumption (T
O-C
)
in the lung with hyperpolarized xenon MR. It
demonstrated that such time constant has a significant
difference between COPD and healthy rats, and we believe
this parameter is helpful to quantify the oxygen
concentration in oxygen therapy of patients.
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