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Abstract #4027

THE INFLUENCE OF VIBRATION FREQUENCY AND IMAGING PLANE ON STIFFNESS MEASUREMENTS IN RENAL MAGNETIC RESONANCE ELASTOGRAPHY

Gavin Low 1,2 , Nicola Eve Owen 3 , Ilse Joubert 1 , Andrew J Patterson 1 , Martin J Graves 1 , Graeme J.M. Alexander 3 , and David J Lomas 1

1 Radiology, Addenbrooke's Hospital, Cambridge, England, United Kingdom, 2 University of Alberta, Edmonton, Alberta, Canada, 3 Hepatology & Gastroenterology, Addenbrooke's Hospital, Cambridge, England, United Kingdom

The purpose of this study was to evaluate the influence of vibration frequency and imaging plane on stiffness measurements in renal magnetic resonance elastography (MRE). Coronal 90-Hz and 60-Hz, sagittal 90-Hz and axial 90-Hz MRE sequences of the kidneys were performed in 12 patients on a 1.5-T MRI. The MRE measured renal stiffness on different vibration frequencies (90-Hz versus 60-Hz) and different imaging planes (coronal versus sagittal oblique versus axial projection) were compared to determine the influence of these variables. A significant difference in renal stiffness was found between frequencies (p = 0.003) and between imaging planes (p < 0.001).

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