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Abstract #4048

Clinical feasibility of motion compensation for MR-based thermometry for treatment in the head and neck region using magnetic resonance-guided focused ultrasound

Samuel Pichardo 1,2 , Justin Lee 3 , and Kullervo Hynynen 4

1 Thunder Bay Regional Research Institute, Thunder Bay, ON, Canada, 2 Electrical Engineering & Physics, Lakehead University, Thunder Bay, Ontario, Canada, 3 Odette Cancer Centre, Toronto, Ontario, Canada, 4 Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada

We propose to use Magnetic resonance image (MRI) guided high intensity focused ultrasound (MRgHIFU) as an adjuvant therapy to radio-therapy for the treatment of recurrent head and neck tumours. A previous pre-clinical study using a porcine model showed the importance of artifacts in MR-based temperature calculation and a method was developed and tested to compensate this source of noise. This paper presents the first results of using this method in a clinic context with patients with primary cancer in the neck area.

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