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Abstract #4049

The changes of uterine fibroids diffusion and perfusion status after MR-guided HIFU ablation evaluated from IVIM MR imaging with different b-values combination

Jia Liu 1 , Bilgin Keserci 2 , Juan Wei 3 , Queenie Chan 4 , Yu Zhang 5 , Rong Rong 1 , and Xiaoying Wang 1

1 Radiology, Peking University First Hospital, Beijing, Beijing, China, 2 Philips Healthcare, Seoul, Korea, 3 Philips Research China, Shanghai, China, 4 Philips Healthcare, Hong Kong, China, 5 Philips Healthcare, Beijing, China

Multiple b-values DWI scan was performed on all 23 patients before and 6 months after HIFU ablation of fibroids using 3.0 T MR acquisition systems. For all b-values no larger than 100 s/mm2 and 200 s/mm2, mono-exponential model was used to calculate the diffusion coefficient respectively. For all b-values, bi- exponential IVIM model was used to calculate D, D* and f. Fibroids diffusion increased apparently accompanied with less microcirculation perfusion 6 months after HIFU treatments. IVIM MR imaging may serve as a valuable tool in emphasizing such diffusion and perfusion changes by using all b-values and/or low b-values no larger than 100 s/mm2.

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