Abstract #4073
Whole Liver Fat Quantification in Pediatric Patients with NonAlcoholic Fatty Liver Disease (NAFLD)
Xiaodong Zhong 1 , Jie Deng 2,3 , Brian M. Dale 4 , Cynthia K. Rigsby 2,3 , and Mark H. Fishbein 5
1
MR R&D Collaborations, Siemens Healthcare,
Atlanta, GA, United States,
2
Department
of Medical Imaging, Ann & Robert H. Lurie Childrens
Hospital of Chicago, Chicago, IL, United States,
3
Department
of Radiology, Feinberg School of Medicine, Northwestern
University, Chicago, IL, United States,
4
MR
R&D Collaborations, Siemens Healthcare, Cary, NC, United
States,
5
Division
of Gastroenterology, Hepatology, and Nutrition, Ann &
Robert H. Lurie Childrens Hospital of Chicago, Chicago,
IL, United States
In this work, a fat quantification mapping technique was
evaluated in pediatric patients with suspected or
identified NAFLD. This technique was capable of
providing whole liver fat quantification in a single
breath-hold and accounting for various factors such as
T2* decay, T1 bias, multi-peak fat modeling. Preliminary
results showed consistency between the proton density
fat fraction results measured with this mapping approach
and a previously validated ROI fitting method. This fat
quantification mapping technique may have great
potential for efficiently evaluating the hepatic
steatosis for liver diseases in pediatric patients.
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