Meeting Banner
Abstract #4074

Optimization of the fat fraction and T2* measurements in mice at 4.7T with the IDEAL algorithm

Roberto Salvati 1,2 , Pierre-Antoine Eliat 3 , Orlando Musso 4,5 , Christine Perret 6 , Eric Hitti 1,2 , Marie Sicard 4,5 , Herve Saint-Jalmes 1,2 , and Giulio Gambarota 1,2

1 LTSI, Universit de Rennes 1, Rennes, France, 2 INSERM, UMR 1099, Rennes, France, 3 PRISM-Biosit CNRS UMS 3480, Universit de Rennes 1, INSERM UMS 018, Rennes, France, 4 Universit de Rennes 1, Rennes, France, 5 Institut National de la Sant et de la Recherche Mdicale, Unit 991, Liver Metabolisms and Cancer, Rennes, France, 6 Oncogense de l'pithlium digestif, INSERM UMRS 1016, Institut Cochin, Paris, France

Fat fraction (FF) and T2* relaxation time are important biomarkers in a number of pathologies (metabolic syndrome, hemochromatosis, etc.). The IDEAL approach (Iterative Decomposition with Echo Asymmetry and Least squares estimation) allows the joint estimation of both FF and T2*. A parameter of this algorithm is the number of echoes to be acquired for an optimal reconstruction of the outputs (FF and T2*). The aim of the current work is to compare the fat fraction as well as T2* values calculated with the 6-echo and 15-echo reconstruction on mice at 4.7T.

This abstract and the presentation materials are available to members only; a login is required.

Join Here