Abstract #4074
Optimization of the fat fraction and T2* measurements in mice at 4.7T with the IDEAL algorithm
Roberto Salvati 1,2 , Pierre-Antoine Eliat 3 , Orlando Musso 4,5 , Christine Perret 6 , Eric Hitti 1,2 , Marie Sicard 4,5 , Herve Saint-Jalmes 1,2 , and Giulio Gambarota 1,2
1
LTSI, Universit de Rennes 1, Rennes,
France,
2
INSERM,
UMR 1099, Rennes, France,
3
PRISM-Biosit
CNRS UMS 3480, Universit de Rennes 1, INSERM UMS 018,
Rennes, France,
4
Universit
de Rennes 1, Rennes, France,
5
Institut
National de la Sant et de la Recherche Mdicale, Unit
991, Liver Metabolisms and Cancer, Rennes, France,
6
Oncogense
de l'pithlium digestif, INSERM UMRS 1016, Institut
Cochin, Paris, France
Fat fraction (FF) and T2* relaxation time are important
biomarkers in a number of pathologies (metabolic
syndrome, hemochromatosis, etc.). The IDEAL approach
(Iterative Decomposition with Echo Asymmetry and Least
squares estimation) allows the joint estimation of both
FF and T2*. A parameter of this algorithm is the number
of echoes to be acquired for an optimal reconstruction
of the outputs (FF and T2*). The aim of the current work
is to compare the fat fraction as well as T2* values
calculated with the 6-echo and 15-echo reconstruction on
mice at 4.7T.
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