Fast 1 H-MRS measurement of pancreatic fat content in a single breath-hold

A relaxation corrected fat fraction (ff) was measured in the human pancreas in one breath-hold, avoiding breathing motion artifacts. Volume and position of the pancreas make the measurement within one breath-hold challenging, but using short repetition rates a series of TE could be recorded with signal averaging in one breath hold. Estimates of water and fat T1s were incorporated by recording fully relaxed scans and used for saturation correction of the signals. Twenty subjects were examined yielding T2 and T1 corrected ff measurements the human pancreas and estimated of the T1 and T2 of pancreatic water and fat signals.

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