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Abstract #4251

Simultaneous acquisition of transverse relaxation, perfusion, and diffusion information of lower-leg muscle using diffusion EPI with different TE

Makoto Terazono 1 , Tosiaki Miyati 1 , Naoki Ohno 1 , Shuya Fujihara 1,2 , Natsumi Makino 3 , Satoshi Kobayashi 4 , and Toshifumi Gabata 4

1 Division of health sciences, Graduate school of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan, 2 Department of Radiology, Shinshu University Hospital, Nagano, Nagano, Japan, 3 School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa, Ishikawa, Japan, 4 Department of Radiology, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan

To simultaneously acquire information on R2, MBF, and restricted water diffusion in lower-leg, we devised a method using SE-diffusion-EPI imaging with different echo times, and compared these values before and after the exercise. R2, ADCr, ADCP, and Fp of the tibialis anterior (TA) of the lower-leg muscle after the exercise were significantly higher than those before the exercise. On the other hand, there was no significant correlation between R2, ADCr, ADCP, and Fp of the TA. Our method makes it possible to simultaneously obtain R2, MBF, and restricted water diffusion in lower-leg, and increase amount of the muscle functional information.

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