Brain changes in end-stage renal disease patients with hemodialysis: a voxel-based analysis of morphometry and CBF based on cognition assessment
Bo Hou 1 , Ke Zheng 2 , Hui You 1 , Jing Yuan 3 , Hai-yun Wang 2 , Xue-mei Li 2 , and Feng Feng 1
Department of Radiology, Peking Union
Medical College Hospital, Beijing, Beijing, China,
of Nephrology, Peking Union Medical College Hospital,
of Neurology, Peking Union Medical College Hospital,
Cognitive impairment is common in individuals with
chronic kidney disease (CKD), while relative studies are
not so abundant as other degenerative diseases. With VBM
and voxel-based analysis of CBF generated with ASL, this
study compared GM, WM and CBF changes between CKD
patients with and without cognitive impairment, and
revealed some significant brain changes in cognition
impaired patients treated with long term hemodialysis.
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