Abstract #4291
Detection of the local volumes of white matter lesions in type 2 diabetes mellitus by an automatic measurement method
Xiaoling Zhang 1 , Bundy Wong 2 , Min Tang 1 , Sipan Chen 1 , Defeng Wang 2 , and Jian Yang 3
1
Department of Radiology, Shaanxi Provincial
People's Hospital, Xi'an, Shaanxi, China,
2
Department
of Imaging and Interventional Radiology, The Chinese
University of Hong Kong, New Territories, Hong Kong,
3
Department
of Radiology, Xi'an Jiao Tong University, Xi'an,
Shaanxi, China
The aim of this study was to assess the volumes of white
matter lesions (WMLs) of T2DM on MRI using an automatic
quantification method, and to explore the relationship
of T2DM and WMLs, and some characteristic change of WMLs
in T2DM. 26 patients with T2DM and 28 healthy persons
underwent MRI including T1WI and FLAIR sequences. The
total volume of WMLs in T2DM group, especially volumes
of WMLs in bilateral frontal lobes and parietal lobe
assessed by an automatic measurement method were
significantly larger than those in control group, and
HbA1c, Systolic and Diastolic BP were correlated with
the WMLs volume in frontal and bilateral parietal lobe
in the T2DM group, which maybe associate with the
cognitive dysfunction.
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