Abstract #4325
Changes of Indices in Diffusion Tensor Images of Patients with Depressive Symptoms in the Elderly with Dementia
Tsung-Yuan Li 1 , Ni-Jung Chang 1 , Wei-Che Wu 2 , Jyh-Wen Chai 1,3 , and Clayton Chi-Chang Chen 1,4
1
Department of Radiology, Taichung Veterans
General Hospital, Taichung, Taiwan, Taiwan,
2
Department
of Psyciatry, Taichung Veterans General Hospital,
Taichung, Taiwan, Taiwan,
3
College
of Medicine, China Medical University, Taichung, Taiwan,
Taiwan,
4
Department
of Biomedical Engineering, Hung Kuang University,
Taichung, Taiwan, Taiwan
The changes of indices in diffusion tensor images (DTI)
of patients with dementia are well-discussed in recent
years. However, the comorbidity of dementia and
depression was observed. In this study, we focused on
the white matter changes associated with depressive
symptoms in dementia and the relationship between DTI
indices and cognitive functions in depressed and
non-depressed patients. By an ROI-based analysis of the
indices in DTI, we investigated the differences between
patients of dementia with depression and without
depression. Furthermore, we correlate the differences
with the score of some clinical cognitive test to figure
out the subtle differences.
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