Meeting Banner
Abstract #4325

Changes of Indices in Diffusion Tensor Images of Patients with Depressive Symptoms in the Elderly with Dementia

Tsung-Yuan Li 1 , Ni-Jung Chang 1 , Wei-Che Wu 2 , Jyh-Wen Chai 1,3 , and Clayton Chi-Chang Chen 1,4

1 Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan, 2 Department of Psyciatry, Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan, 3 College of Medicine, China Medical University, Taichung, Taiwan, Taiwan, 4 Department of Biomedical Engineering, Hung Kuang University, Taichung, Taiwan, Taiwan

The changes of indices in diffusion tensor images (DTI) of patients with dementia are well-discussed in recent years. However, the comorbidity of dementia and depression was observed. In this study, we focused on the white matter changes associated with depressive symptoms in dementia and the relationship between DTI indices and cognitive functions in depressed and non-depressed patients. By an ROI-based analysis of the indices in DTI, we investigated the differences between patients of dementia with depression and without depression. Furthermore, we correlate the differences with the score of some clinical cognitive test to figure out the subtle differences.

This abstract and the presentation materials are available to members only; a login is required.

Join Here