Abstract #4334
Describing the distribution of myelin water fraction change among early stage MS lesions
Elizabeth Monohan 1 , Wendy Vargas 1 , Sneha Pandya 2 , Michael Dayan 2 , Thanh Nguyen 2 , Ashish Raj 2 , Sandra Hurtado 3 , and Susan Gauthier 1
1
Neurology and Neuroscience, Weill Cornell
Medical College, New York, NY, United States,
2
Radiology,
Weill Cornell Medical College, New York, NY, United
States,
3
Public Health, Weill Cornell Medical
College, New York, New York, United States
Our study utilized FAST-T2, a T2-relaxometry technique,
to study myelin water fraction (MWF) within two types of
early MS lesions: enhancing and new non-enhancing T2
lesions. Additionally, we exploited the T2 spectrum and
utilized a novel approach to measure resolving edema
within these lesions types. Enhancing lesions showed a
greater and more variable change in MWF on follow up
scan versus new non-enhancing lesions.
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