Abstract #4359
Cortical abnormalities in multiple sclerosis by 7T MRI: Novel imaging insights and update
Yulin Ge 1 , Ilya Kister 2 , Sanjeev Chawla 1 , Tim Sinnecker 3 , Jean-Christophe Brisset 1 , Joseph Herbert 2 , Friedemann Paul 3 , and Jens Wuerfel 3
1
Radiology, NYU Langone Medical Center, New
York City, NY, United States,
2
Neurology,
NYU Langone Medical Center, New York, United States,
3
Universittsmedizin
Gttingen, Berlin, Germany
In vivo evaluation of cortical pathology is still
currently challenging. Using ultra-high field 7T MRI,
this study showed different types of cortical lesions
that are not visible on conventional field-strength MRI,
and updated lesion signal, morphology, and the extent of
cortical involvement. In particular, higher prevalence
of hypointense cortical lesions found in this study may
have critical clinical value regarding hemorrhagic
susceptibility or unfavorable drug effects in MS
patients.
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