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Abstract #4456

Oxygen-enhanced T2* cardiac magnetic resonance imaging in non-ischemic cardiac diseases

Satoshi Kawanami 1 , Michinobu Nagao 1 , Masato Yonezawa 2 , Yuzo Yamasaki 2 , Takeshi Kamitani 2 , Torahiko Yamanouchi 2 , Tomomi Ide 3 , Ryohei Funatsu 4 , Hidetake Yabuuchi 5 , and Hiroshi Honda 2

1 Molecular Imaging & Diagnosis, Kyushu University, Graduate School of Medicine, Fukuoka, Fukuoka, Japan, 2 Clinical Radiology, Kyushu University, Graduate School of Medicine, Fukuoka, Fukuoka, Japan, 3 Cardiovascular Medicine, Kyushu University, Graduate School of Medicine, Fukuoka, Fukuoka, Japan, 4 Radiological Technology, Kyushu University Hospital, Fukuoka, Fukuoka, Japan, 5 Health Sciences, Kyushu University, Graduate School of Medicine, Fukuoka, Fukuoka, Japan

In this study, we analyzed T2* value in the mid-left ventricular septum avid both normoxia and hyperoxia among clinical cases with non-ischemic heart disease. The oxygen-enhanced T2* cardiac magnetic resonance (CMR) was promising to evaluate the myocardial blood-oxygen dependent (BOLD) response to hyperoxia. The development of quantitative evaluation technique for the oxygen metabolism in human myocardium in vivo has opened up new avenues for the study of the cardiac pathophysiology. To our knowledge, this is the first clinical study that has assessed the myocardial T2* response to hyperoxic respiratory challenge by BOLD-CMR.

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