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Abstract #4464

Improved Arrhythmia-Insensitive-Rapid (AIR) cardiac T 1 Mapping with Pulse Sequence Optimization: k-space Ordering and Flip Angle

Kyungpyo Hong 1,2 and Daniel Kim 1

1 UCAIR, Department of Radiology, University of Utah, Salt Lake City, Utah, United States, 2 Department of Bioengineering, University of Utah, Salt Lake City, Utah, United States

Arrhythmia-insensitive-rapid (AIR) cardiac T 1 mapping pulse sequence is a promising method for imaging patients with rapid heart rates and/or arrhythmia. We sought to improve further AIR cardiac T 1 mapping through k-space ordering and flip angle optimization. In human volunteers and patients, centric k-space ordering acquisitions yielded image artifacts arising from eddy currents, whereas centric-pair k-space ordering acquisitions suppressed image artifacts. For flip angles ranging from 25-65, standard deviation decreased with flip angles, with significant difference in mean T 1 values for any of the 4 types of measurement (native myocardial T 1 , native blood T 1 , post-contrast myocardial T 1 , and post-contrast blood T 1 ).

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