Alzheimer's disease (AD) is a progressive neurodegenerative
disorder. Currently no definite treatment available for AD. We have examined
the efficacy of Rasa Sindoor, an Ayurvedic formulation, for the improvement of
memory and neuronal activity in AβPP-PS1 mouse model of AD. Neuronal metabolism
was followed by 1H-[13C]-NMR spectroscopy together with
an infusion of [1,6-13C2]glucose. Our results indicate
that the Rasa-Sindoor improved memory,
and excitatory and inhibitory neuronal metabolic activity in AD mice.