Abstract #0163

Quantitative Liver Function Analysis using Volumetric T1 Mapping with Fast Multi-Slice B1 Correction on Hepatocyte-specific Contrast Enhanced Liver Magnetic Resonance Imaging

Jeong Hee Yoon¹, Jeong Min Lee¹, Eun Ju Kim², Tomoyuki Okuaki³, and Joon Koo Han¹

¹Radiology, Seoul National University Hospital, Seoul, Korea, Republic of, ²Philips Healthcare, Seoul, Korea, Republic of, ³Philips Healthcare, Tokyo, Japan

Liver signal intensity on hepatobiliary phase at gadoxetic acid-enhanced liver MRI has been reported to be useful to estimate global and regional liver function quantitatively. However, simple MR signal measurement is often suffering from its sensitivity of MR field inhomogeneity and non-linear relationship with contrast medium concentration. Herein, we investigated of B1 correction effect on T1 map and compared its diagnostic performance to assess liver function according to Child-Pugh classification. In addition, we attempted to investigate risk assessment capability of B1 corrected T1 map for long-term clinical outcome in patients with cirrhosis.

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