Abstract #0164

Gd-EOB-DTPA-enhanced MRI: evaluation of liver function by multiple hepatocyte-phase images and T1 mapping in rats

Jia Xu¹, Xuan Wang¹, Yan You², Qin Wang¹, Hui Liu³, Jing Lei¹, Huadan Xue¹, and Zhengyu Jin¹

¹Department of Radiology, Peking Union Medical College Hospital, Beijing, China, People's Republic of, ²Department of Pathology, Peking Union Medical College Hospital, Beijing, China, People's Republic of, ³Siemens Ltd. China, Shanghai, China, People's Republic of

To evaluate regional liver function preoperatively is of great value in planning surgical management. Our Aim is to investigate the potential of Gd-EOB-DTPA enhanced MRI in evaluating hepatic function in rats with liver fibrosis. Parameters calculated from Gd-EOB-DTPA enhanced MRI exhibited moderate to high correlation with plasma indocyanine green retention rate at 15 minutes after intravenous injection of ICG (ICG R15) in rats with liver fibrosis, indicating its potential in liver function evaluation.

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