Abstract #0240

Variable Density Magnetization Transfer (vdMT) imaging for 7 T MR Imaging

Se-Hong Oh¹, Wanyong Shin¹, Jongho Lee², and Mark J. Lowe¹

¹Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, ²Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of

Because of the much higher SAR and longer acquisition time, in-vivo studies using MT at UHF have not been clinically feasible. In this work, we demonstrated a new approach (variable density MT [vdMT])for acquiring whole brain covered 7T MT data in a clinically reasonable time. vdMT provides similar image quality to that obtained with conventional MT imaging, and shortens the scan time by avoiding from SAR limitation. The proposed method generates high-resolution MT data in reasonable scan time and it exhibits high similarity with the conventional method. Moreover, it maintains sensitivity to MS lesions.

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