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Abstract #0240

Variable Density Magnetization Transfer (vdMT) imaging for 7 T MR Imaging

Se-Hong Oh1, Wanyong Shin1, Jongho Lee2, and Mark J. Lowe1

1Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, 2Laboratory for Imaging Science and Technology, Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of

Because of the much higher SAR and longer acquisition time, in-vivo studies using MT at UHF have not been clinically feasible. In this work, we demonstrated a new approach (variable density MT [vdMT])for acquiring whole brain covered 7T MT data in a clinically reasonable time. vdMT provides similar image quality to that obtained with conventional MT imaging, and shortens the scan time by avoiding from SAR limitation. The proposed method generates high-resolution MT data in reasonable scan time and it exhibits high similarity with the conventional method. Moreover, it maintains sensitivity to MS lesions.

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