Abstract #0257

Measurement and Compensation of Respiration-Induced B0 Variations for Bone Marrow Fat Quantification in Lumbar Spine

Yoonho Nam¹, Joon-Yong Jung¹, Hyun Seok Choi¹, Eojin Hwang¹, Hongpyo Lee², and Dong-Hyun Kim²

¹Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ²Department of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of

Fat fraction of the bone marrow has been suggested as an important quantitative parameter in the assessment of treatment response and determination of the benignity in oncologic imaging. Therefore, accurate fat quantification is a prerequisite for the fat fraction to be established as a reliable imaging biomarker. For this purpose, spoiled gradient echo sequences have been commonly used. However, gradient echo imaging is susceptible to B₀ variations from various sources such as respiration, cardiac pulsation. In this study, we investigate and compensate the effects of respiration-induced B₀ variations on fat quantification of the bone marrow in the lumbar spine.

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