Meeting Banner
Abstract #0258

Quantitative Muscle Perfusion with DCE-MRI Shows Distinct Load-Dependent Exercise-Stimulated Muscle Perfusion Patterns

Jeff L. Zhang1, Christopher Hanrahan1, Christopher C. Conlin1, Corey Hart2, Gwenael Layec2, Kristi Carlston1, Daniel Kim1, Michelle Mueller3, and Vivian S. Lee1

1Radiology, University of Utah, Salt Lake City, UT, United States, 2Internal Medicine, University of Utah, Salt Lake City, UT, United States, 3Vascular surgery, University of Utah, Salt Lake City, UT, United States

Noninvasive mapping of calf muscle perfusion with high spatial resolution has potential for assessing the severity of peripheral artery disease (PAD) and studying associated capillary density abnormality. We tested our novel DCE-MRI method to measure calf muscle hyperemia stimulated by plantar flexion at three different workloads. Increases in exercise load caused increased total perfusion in gastrocnemius, with a heterogeneous pattern at medium load and homogeneous at higher load. Perfusion in soleus did not increase until very heavy load of 16 lbs. DCE-MRI provides high spatial resolution measurement of post-exercise muscle perfusion.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords